Uterine natural killer cells initiate spiral artery remodeling in human pregnancy

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Uterine natural killer cells initiate spiral artery remodeling in human pregnancy.

Uterine spiral artery remodeling is required for successful human pregnancy; impaired remodeling is associated with pregnancy complications, including late miscarriage, preeclampsia, and fetal growth restriction. The molecular triggers of remodeling are not known, but it is now clear that there are "trophoblast-independent" and "trophoblast-dependent" stages. Uterine natural killer (uNK) cells ...

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ژورنال

عنوان ژورنال: The FASEB Journal

سال: 2012

ISSN: 0892-6638,1530-6860

DOI: 10.1096/fj.12-210310